Left ventricular hypertrophy: pathogenesis, detection, and prognosis. The hypertension pandemic: an evolutionary perspective. Trends in prevalence and control of hypertension according to the 2017 American College of Cardiology/American Heart Association (ACC/AHA) Guideline. This suggests that calcium supplementation for postmenopausal women with hypertension requires the close observation of blood pressure to prevent any further increase, especially in women who are being treated with calcium channel blockers ( registration: NCT04618952).ĭorans KS, Mills KT, Liu Y, He J. The present results differ from those of previous studies. Among patients who had been using calcium channel blockers, calcium and vitamin D supplementation caused a notable increase compared to baseline systolic ( p = 0.019) and diastolic blood pressures ( p = 0.001).
The changes in both the mean systolic ( p = 0.047) and diastolic blood pressure ( p = 0.015) were suggestive of an increase in blood pressure after consuming calcium and vitamin D supplements. We used 24-h ambulatory blood pressure monitoring to record the initial and final blood pressure in all participants.
The study period was 8 weeks with close follow-up. This triple-blind randomized clinical trial enrolled 98 women of postmenopausal age with hypertension in 2019. In this study, we assessed the effect of calcium and vitamin D supplementation on the blood pressure of postmenopausal women with hypertension as a population group in which the use of calcium supplements is prevalent. However, the results to date remain controversial. Many studies have demonstrated a weak correlation between the consumption of calcium (or calcium plus vitamin D) and blood pressure, suggesting that calcium supplements might reduce blood pressure. Hypertension is a highly prevalent disease with serious cardiovascular and renal complications.
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